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The mechanism is intuitive
Primary Handling Editor: Karen OLeary, in collaboration with the Nature Medicine team
Ozempic and Mounjaro are FDA-approved diabetes drugs comprised of semaglutide, prescribed primarily for treatment of type 2 diabetes
Several possible reasons for the lack of efficacy of antioxidants in clinical trials include (i) insufficient antioxidant levels in the target organ, especially in the nervous system, because an integrated bloodbrain barrier (BBB) is a major obstacle to delivering desired substances, including antioxidants, into the CNS
Male study subject, 26 years old, diagnosed with AGA, Norwood IV
No funding bodies had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
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