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Additionally, new or worsening constipation accompanied by unexplained weight loss (beyond expected therapeutic weight reduction), persistent changes in stool caliber, or alternating constipation and diarrhea warrants evaluation to exclude structural or neoplastic causes, particularly in patients age 45 or older or those with family history of colorectal cancer
While these two medications work through very different pathways in the body, they are sometimes used together to provide a multi-layered approach to weight management
CagriSema (cagrilintide + semaglutide) This is the one closest to reaching approval and pharmacy shelves
Presented for research literature review only Xie J et al
It's been on the market for 60, 70 years now, maybe a little longer
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