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However, another approach could be to increase endogenous GLP-1 production by regulating the transcription of the PG gene in intestinal endocrine L cells 6
& Jaattela, M
Berberine is not recommended for long term use, without breaks, this is because there is limited support to confirm its safety beyond this period
References to notoriety bias in the Discussion therefore reflect conceptual mechanisms well described in spontaneous reporting systems during periods of regulatory or media attention, rather than empirical temporal testing
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