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So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets
Preclinical research suggests it supports tissue repair, reduces inflammation, and modulates key biological healing pathways across multiple organ systems
With consistent use, skin appears significantly firmer, smoother, and more contoured
and Bhatt et al.)