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Saxenda's mechanism of action includes glucose-dependent insulin secretion and suppression of glucagon release, leading to improved blood glucose regulation

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2004 Mar;134(3):48992

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To determine whether these exposure levels result in significant changes in GIPR function, a cAMP assay was used to determine the IC 50 of mGIPR-Ab in mouse Neuro2A cells (Extended Data Fig

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This makes the GCGR component particularly relevant for research into non-alcoholic fatty liver disease (NAFLD) models and energy balance studies

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