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An increase in LPP increases microvascular leakage, thereby reducing the bioavailability of drugs such as paclitaxel to tumor cells [49]

Protocol 2: The modified standard schedule This approach starts at or near the standard dose but extends the time between escalations

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Bag 1: Electrolytes, amino acids, vitamins & antioxidants Bag 2: NAD+ infusion administered separately The amino acid blend helps provide protein-building support, while NAD+ supports cellular energy pathways and enzymes such as SIRT1 and SIRT2, which are involved in metabolism, cellular repair, vascular function, and stress response

Ice the injection site for 30 to 60 seconds before injecting

SID, steroid-induced diabetes