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A 2024 Science Advances paper from Christian Hendershot and colleagues tested semaglutide in 48 adults with alcohol use disorder over 9 weeks and found significant reductions in alcohol consumption, craving, and heavy drinking days, along with reductions in cigarette craving as a bonus endpoint

Particles can form from crystallization of the medication, precipitation of inactive ingredients, contamination from the rubber stopper, or introduction of foreign material during use

Trial highlights: - Weight reduction: Patients achieved up to ~24% mean body weight loss at 48 weeks

doi: 10.1001/jamanetworkopen.2021.44973 191 MuteebGRehmanMTShahwanMAatifM

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These benefits occur as Vitamin B12 produces red blood cells and improves nervous system