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To explore through an alternative strategy whether GLP-1R binding kinetics influence PM recycling and insulin secretion, we utilized the GLP-1R allosteric modulator 4-(3-( b enzyloxy)phenyl)-2-( e thylsulfinyl)-6-( t rifluoro-methyl) p yrimidine (BETP), which alters the residence time of orthosteric GLP-1R agonists 45
However, due to its extremely short life of a few minutes, GLP-1 hormone cannot produce lasting effects
To account for design effects, the statistical computing package R and the library package survey were used to calculate standard errors
This article surfaces that conflict directly rather than repeating just one figure
[16], who demonstrated that treatment of hASC with 100 nM Ex-4 led to a significant reduction in Hoechst-positive cells, reduced DNA fragmentation, and fewer cells entering early stages of apoptosis
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