These include certain antipsychotics (olanzapine, clozapine), mood stabilizers (valproate, lithium), antidepressants (mirtazapine, paroxetine), corticosteroids, and some diabetes medications like insulin or sulfonylureas
Lancet 366 , 649659 (2005)
It is involving the endocrine cells of the gastrointestinal tract and their action as a possible therapeutic target for Type 2 Diabetes Mellitus due to their activation of GLP-1, which results in a hypoglycemic impact [17]
Tresiba has been shown to be cardiovascular-safe (non-inferior to placebo) in the DEVOTE trial, but it has not demonstrated the cardiovascular benefit that GLP-1 medications provide
Scientific References Falutz J
The FDA is challenging European firms on the rigor of their internal audits and vulnerability assessments