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When patients aged 50 years old start triple therapy, event-free survival was estimated to increase by 3.2 years (95% CI 2.14.3 years) for MACE, 3.2 years (95% CI 2.44.0 years) for HHF, and 5.5 years (95% CI 4.06.7 years) for CKD progression compared with that for conventional therapy alone
doi: 10.1007/s11154-008-9101-5 40 HanefeldMFleischmannHSiegmundTSeufertJ
None of this handling detail changes the evidence picture
Microdosing these medications may carry several potential risks, including reduced efficacy and unforeseen side effects
2015 Jan 20;144(2):73-9.
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