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When disorders of fatty acid -oxidation metabolism and abnormalities of branched-chain amino acid metabolism occur, characteristic alterations of one or more acyl carnitines occur

WHO and EMA Warnings About Semaglutide and NAION In June 2025, the World Health Organization alerted healthcare professionals and regulatory authorities to the risk of non-arteritic anterior ischemic optic neuropathy (NAION) associated with semaglutide medications, including Ozempic, Rybelsus, and Wegovy

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Another study (Sun et al., 2020) demonstrated that serum fibroblast growth factor 19 (FGF19) and bile acid levels were simultaneously increased in patients with T2DM early in life

N Engl J Med 2023;389:222132.ArticlePubMed 73

GLP-1 receptor agonists in binge eating disorder: a narrative review