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In white adipose tissue of obese, insulin-resistant and aged mammals, NNMT is dramatically upregulated and because it consumes both the universal methyl donor (SAM) and the NAD precursor (nicotinamide), its hyperactivity simultaneously depletes the cellular methylation reserve and the NAD-salvage pool [1,2]

Consult your doctor before use if you have a history of allergies, kidney problems, or low potassium

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Stubborn fat areas have unfavorable ratios