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CJC-1295 activates the GHRH receptor on pituitary somatotrophs

Save Tesamorelin is a synthetic analog of growth-hormone-releasing hormone (GHRH) with the strongest human evidence for reducing visceral fat 15-18% reductions in HIV-associated lipodystrophy trials (Falutz et al., NEJM 2007)

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Mechanistic studies originally focused on its ability to dampen neuronal hyperexcitability by potentiation of inhibitory neurotransmission

Understanding antioxidant mechanisms helps optimize GHK-Cu protocols