It's the form supported by the largest body of research, it's exceptionally stable in storage, which matters for consistent potency across batches, and it's the form most clinics and pharmacies use as a result
Presented for research literature review only Thompson JE et al
Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight (STEP-3)
Even small amounts of degradation products or synthesis impurities can introduce unintended receptor interactions or background signaling activity that complicates interpretation in receptor binding assays, metabolic pathway studies, and cell-based experiments
But several effects show up specifically in women or present differently: Hair shedding
Two ml aqueous 5 millimolar Tris buffer solution at pH 7.5, and containing antioxidants are added to the flask containing the dried lipid film