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Other peptides worth comparing: Liraglutide daily GLP-1 agonist, less effective than both but FDA-approved since 2014 Retatrutide triple agonist (GLP-1/GIP/Glucagon), showing up to 24% weight loss in Phase 2 trials AOD-9604 HGH fragment for fat metabolism, much milder effect The Bottom Line Tirzepatide has the edge in raw efficacy and tolerability based on trial data

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When appropriately prescribed and monitored, these regimens contribute to improved satiety, better glycaemic control, and maintenance of functional MM, thereby preventing sarcopenic obesity and reducing the risk of weight regain

Read this way, the dose numbers are context rather than a prescription

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So, your body cannot use your stored fats for energy