The activation of TLR-4/NF-B signaling in LPS-caused injury in chondrocytes mediated the inflammatory and proapoptotic actions of Gal-3 while Gal-3 silence resulted in apoptosis inhibition through inhibition of the inflammatory response (Wang et al., 2019)
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Gastroenterology 135 , 19841992 (2008)
A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death
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