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First publicly characterized by Coskun et al

Practical Research Considerations A few practical points come up repeatedly in the research literature and community discussion: Weekly cadence

Some patients report a slight mineral taste in their mouth or a cool sensation in their armthis is completely normal

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Children can get disability if their condition "meets or functionally equals" a listed impairment

Furthermore, there is a lack of randomized controlled trials, standardized outcome measures, and long-term follow-up reports