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Several GLP-1RAs CVOTs included patients with chronic kidney disease and showed consistent cardiovascular and some renal benefits
Body Weight Reduction Body weight, from a mean baseline of 95.2 kg, was reduced by 4.6 kg and 2.3 kg in semaglutide 0.5 mg and dulaglutide 0.75 mg, respectively, while in semaglutide 1.0 mg and dulaglutide 1.5 mg, it was reduced by 6.5 kg and 3.0 kg, respectively
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Naturally produced in the liver, it plays a central role in neutralizing free radicals, detoxifying harmful compounds, and supporting immune function
Nat Commun 2012
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