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A variety of factors can put someone at risk for a nutrient deficiency, including: Inadequate diet Increased nutrient demands due to pregnancy, breastfeeding, and menstruation Decreased nutrient absorption from GI conditions like celiac and Crohn's disease Genetic mutations (like the MTHFR polymorphism) Lower bioavailability of some nutrients (e.g., zinc and iron) from plant versus animal sources Decreased synthesis of vitamin D from sunlight among individuals with dark-colored skin Common medications that impact nutrient absorption, metabolism, and excretion Aging, which can trigger changes (such as decreased stomach acid) that decrease vitamin D and B12 absorption Now let's explore seven common nutrient deficiencies that can impact metabolic health and the blood tests that check for these deficiencies

Others have some issues with dose changes and their insurance coverage

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The absence of pharmacokinetic studies, dose-response relationships, or comparative effectiveness data represents a significant evidence gap

JAMA 274 : 15261533

Updated May 15, 2025