DL: Supervision, Conceptualization, Writing original draft, Writing review & editing
Doctors have observed that along with fat loss, a small portion of weight lost on GLP-1 RAs can be fat-free mass (mostly muscle)
This mechanistic distinction is the basis of the well-established synergistic relationship between ipamorelin and GHRH analogues in GH secretion research
Ipamorelin is a selective ghrelin receptor agonist that triggers additional GH release without significantly raising cortisol or prolactin
In a study with eight poorly controlled T2DM patients who received a liquid meal via a nasogastric tube and exogenous infusion of GLP-1 to achieve plasma levels of about 70 pM, gastric volume remained constant over 2 hours, and plasma glucose returned to normal fasting values within 3 4 hours (152)
Sometimes we have a person who's living with a higher BMI and that medication might make the difference for that patient receiving bariatric surgery or not, she said