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Novo signaled deep change by appointing Mike Doustdar as CEO in August, who quickly set a course for 9,000 layoffs at the company worldwide and a major business reboot

Moreover, 31.6% of tirzepatide participants lost 25% of body weight compared to 16.1% of semaglutide participants

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Most notably, the study found no increased risk of hospitalization for DKA (HR = 0.83) or severe hypoglycemia (HR = 0.82) among users compared with non-users, although these safety outcomes were limited to events captured through hospitalization records

doi: 10.1097/PSY.0000000000000537