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From 1957 the dose was adjusted to 1 mg per 7 kilograms of body-weight
We are conscious of the limitations of the animal models [123], however in a clinical trial undertaken by this group to asses IGF-1 in liver function under cirrhosis with these same dosage (20 g/kg/day) no side effects were reported and liver function greatly increased [108]
Chronic stress and alcohol abuse may also indirectly affect B12 levels
Oral supplements are easy but require discipline
The speed at which B12 treats nerve symptoms shows differences between patients
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