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doi:10.3390/healthcare11131946 2

The shortage was real

Multiple other factors, discussed in subsequent sections, may be responsible for respiratory symptoms in this patient population

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Furthermore, it has been reported that tenocytes with IGF-1 (10, 50, and 200 ng/mL) displayed the increased expression of tenocyte-associated structural protein genes for type I collagen (COL1A2), and type III collagen (COL3A1), but this effect is not dose-dependent and highest values were achieved at 50 ng/mL (Caliari and Harley, 2013)