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But a 2026 report published in Diabetes, Obesity and Metabolism suggests the effects of discontinuing treatment extend beyond the scale

Most people begin to see significant weight loss within 4-8 weeks of starting treatment, with optimal results typically achieved after 6-12 months

doi:10.1001/jama.2024.10333 2

It can also help to boost the immune system and improve overall health

These designs have been useful in dissecting which weight-related endpoints depend on IGF-1 and which are truly GH-independent a question of ongoing interest in obesity and metabolic science

Their amino acids also support muscle maintenance during weight loss