Microscopy Images in Figure 2C,D, 3D,E, 5B-G and Figure S1A,B and S4B-J were taken using a laser scanning Leica TCS SP8 confocal microscope fitted with both photomultiplier and hybrid detectors and run using LAS software version X
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TN), under a 12-h light/dark cycle for 5 weeks at the University of Ottawa Heart Institute
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