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10.1186/s40779-018-0179-0 58 MillerB.KimS
2 Oral GLP-1s builds over time
Oncotarget 8 , 114268114280 (2017)
doi: 10.1186/1750-1326-7-12 416 AbdolahiMJafariehASarrafPSedighiyanMYousefiATafakhoriAet al
Pathophysiology of Cardiac Involvement Cardiac manifestations among these patients include cardiomyopathy (hypertrophic, dilated, restrictive), heart rhythm disorders, valvular defects, and congenital heart structure disorders
676 The oncogene c-Myc directly upregulates a suite of glycolytic genes (HK2, PFK1, TPI, GAPDH, ENO, LDHA, and MCT1), intensifies glycolytic flux in cancer cells, 663,677,678 and stabilizes HIF-1 under normoxic conditions by inhibiting its proteasomal degradation through interaction with the von HippelLindau protein
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