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Therapeutic rAAVrh10 mediated SOD1 silencing in adult SOD1G93A mice and nonhuman primates
Apply to clean, dry skin after cleansing, before heavier moisturizers
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Bemark M, Pitcher MJ, Dionisi C, Spencer J
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation [see Drug Interactions (7.2), Use in Specific Populations (8.3), and Clinical Pharmacology (12.3)]
If fractionating, keep membrane and cytosolic fractions clearly separated
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