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Immunohistochemistry of liver sections showed CD36 as located in the hepatocyte plasma membrane in patients with steatosis and NASH, compared to a weak CD36 expression confined to the cytoplasm of hepatocytes in normal livers, suggesting that the translocation of CD36 protein from cytoplasm to membrane may be a triggering event in NAFLD progression [25]

AOD-9604 is a synthetic 16-amino acid peptide fragment derived from the C-terminal region of human growth hormone (amino acids 176-191)

The researchers concluded that there was small improvement, but due to the limited number of patients in the study, firm conclusions could not be drawn

The researchers also suggested that The enhancement of wound closure was more pronounced (median of 89.2% compared with -10.3% for vehicle

(Summarized from Czimmerer et al., 2023