TGR5 and FXR are expressed in enteroendocrine L-cells in the intestine
Comparable immune remodeling has also been implicated in the gutskin [364] and gutbone axes [365], contributing to psoriasis and atopic dermatitis, as well as osteoporosis and bone loss
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GLP-1 is a hormone produced and secreted by intestinal enteroendocrine L cells and certain neurons upon food consumption, which decreases blood glucose by enhancing insulin secretion, reducing glucagon concentrations, and delaying gastric emptying
Food moves more slowly through your stomach, which helps prevent blood sugar spikes and keeps you feeling full longer