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Disulfide bonds are covalent bonds between the sulfur atoms on cysteine side chains, such as in oxidized glutathione (Figure 4)
10.1038/nrneph.2017.123 160
Hashash JG, Thompson CC, Wang AY
Two key contributors: blood sugar reduction (even modest drops can cause tiredness during adaptation) and dehydration, since electrolyte imbalance prevents water from reaching cells even when fluid intake seems adequate
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