For long-term knee osteoarthritis, oral collagen peptides (3-5g daily) have stronger randomized controlled trial support across multiple studies totaling 507 patients
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After homogenisation, tubes were centrifuged for 5 min at 16,000 g at 4C and the obtained supernatant was incubated for 20 min at RT in the dark
In general, in all treated conditions a drastic modulation of the MRAB biofilm architecture was evident, with enhanced disruption and an increase in dead (red) biofilm cells (Figure 3C and Supplementary Figure S3)