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For example, in cardiovascular outcome trials such as LEADER and SUSTAIN-6, small increases in heart rate were documented alongside reductions in major adverse cardiovascular events

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At baseline, most patients (97%) were treated with one or more glucose-lowering medications, including metformin (76%), insulin (51%), SGLT-2i (27%), sulfonylurea (29%), and DPP-4i (23%) with CV disease and risk factors managed with lipid-lowering medications (89%), platelet-aggregation inhibitors including aspirin (77%), angiotensin converting enzyme inhibitors or angiotensin II receptor blockers (79%), and beta blockers (64%)

Contact your GP or diabetes team for a replacement prescription

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