Intriguingly, pharmacological GIPR agonism combined with GLP-1R agonism also involves CNS-GIPR signaling in the control of satiety pathways (15, 16), suggesting rewiring of incretin signaling in obesity
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Through this mechanism, Wegovy: Encourages fullness sooner during meals Reduces persistent hunger between meals Slows digestion to extend satiety For optimal results, clinical teams usually recommend combining Wegovy with a calorie-controlled diet and regular physical activity
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