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However, this result is expected considering the very high activity of glutaredoxins as deglutathionylating enzymes and a decreased GSSR concentration neither excludes mechanism (ii) or (iii) from Fig

Mait establishes realistic timelines based on individual assessment and treatment goals

Severe deficiency : Weekly or biweekly injections may initially be required to correct anemia and neurological symptoms

Glutathionehelps to reduce hyperpigmentation and lightens skin complexion

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It suggests the drug reached the brain and affected disease-relevant pathways, but that timing, magnitude, delivery, or patient selection were insufficient to overcome established neurodegeneration when used as a stand-alone therapy