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This compound can be used as a tracer 2

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GHS-R1a couples primarily to G q/11 , activating phospholipase C (PLC)

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Comparing with wild genotype (CC), the heterozygote (CT) and mutation homozygote (TT) lead to the decline of enzyme activity by about 34 and 75%, and increased thermolability in lymphocyte extracts 25

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