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January 29, 2025 At a Glance GLP-1 users likely need supplements to make up the calorie deficit they experience from the resulting weight loss

Serious side effects are rare but may include allergic reactions, shortness of breath, and severe dizziness

Things You Should Know Clean the injection site with alcohol and a cotton ball

Patients should contact their GP or prescribing clinician if they experience severe or persistent constipation that does not respond to conservative management measures within one to two weeks

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Similarly, in December 2023, Roche agreed to buy GLP-1RA drug developer Carmot Therapeutics for up to $3.1bn