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The study was conducted in accordance with the ethical standards of the 1964 Declaration of Helsinki and its later amendments
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Six months after beginning semaglutide treatment, subjects achieved an average lowering of their HbA1c by 0.77% (from 7.6% to 6.8%) and reduced their body weight by 4.7 kg (from 94.1 kg to 89.7 kg)
Measurement of plasma HbA1c concentration HbA1c concentration in plasma samples collected from DIO mice at 8, 16, and 24 weeks after the initial treatment of the pharmacodynamic study was determined using a mouse HbA1c ELISA kit (Aviva Systems Biology) according to the manufacturers protocols
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