IR given in combination with MT gave similar results to MT alone
Cell line A2780 sensitive (93112519) and A2780 cisplatin resistant (93112517) were obtained from Sigma Aldrich
Hong SJ, Jia SX, Xie P, Xu W, Leung KP, Mustoe TA, et al
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A 2017 review summarised neuroprotective properties of silymarin in animal models, including: Reduction of amyloidogenic activity (relevant in Alzheimer's research) Anti-inflammatory action in nerve tissue Reduction of oxidative stress in the brain Possible positive effects on cognitive function Possible reduction of stroke risk Whether these effects can be achieved in humans at attainable concentrations of silymarin in particular whether sufficient quantities can cross the blood-brain barrier remains unclear
(42) In one study, serum selenium levels in patients with remission and relapse of Graves disease were compared