To further assess the ROS scavenging ability of G/D-CuP, the 2, 7-dichlorofluorescein diacetate (DCFH-DA) fluorescent probe was used to measure intracellular ROS levels
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Gene ontology analysis using the DAVID tool, focusing on the genes upregulated by pefloxacin and whose upregulation was suppressed by dexamethasone co-administration, revealed that several pathways related to oxidative stress, such as response to hydrogen peroxide and hydrogen peroxide catabolic process, were enriched (Figure 5A)
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They found that BPC-157 causes blood vessels to relax and widen, and that this effect depends on the inner lining of the blood vessel and a molecule called nitric oxide