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[7] (This interaction is not significant when levodopa is combined with carbidopa, as in standard carbidopa/levodopa therapy, because carbidopa prevents peripheral levodopa breakdown.) Another notable interaction involves the chemotherapeutic agent altretamine: coadministration of pyridoxine can decrease altretamines effectiveness and is generally advised against unless specifically directed
However, some people may experience dizziness, lightheadedness, or injectionrelated discomfort, especially shortly after administration
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The three recommended injection sites are the abdomen (at least 2 inches from the navel), the front of the thigh, and the back of the upper arm
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