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Elderly patients tend to have a greater frequency of decreased hepatic, renal, or cardiac function, and also have concomitant disease or receiving other drug therapy

Benefits of B12 injections include the following: Might Reduce Depression, Cognitive Decline and Dementia: Some studies show that, especially in older people, supplementing with vitamin B12 can help prevent depression, restore better mood control and retain healthy memory/mental functioning

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The pages linked below present the evidence without reduction

Once mature, the adult-formed granule cells enter into synaptic competition with the pre-existing ones, a competition that concerns both synaptic inputs from the entorhinal cortex and synaptic outputs to the CA3 and CA1 targeted regions [70, 71]

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