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267 Claudin-7 (Cldn-7), a member of the tight junction protein family, is closely related to inflammation and tumor development, and Cldn-7 deficiency can significantly upregulate the expression of -catenin and its downstream target genes c-myc and cyclin D1 by promoting aberrant activation of the Wnt/-catenin pathway, which in turn leads to abnormal cell proliferation and tumorigenesis
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Given these seemingly negative findings, can the combination of GLP1/GIP be helpful in diabetes management
The SCN receives direct light input from intrinsically photosensitive retinal ganglion cells in the eye, which entrains the clock to the external 24-h light/dark cycle each day
Trotman et al
Gastro-oesophageal reflux disease Treatment summaries
