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458 CTLA-4 inhibitor ipilimumab has been approved by the FDA for the treatment of advanced metastatic melanoma, while it also exhibited modest antitumor activity observed in TNBC

In a rat ischemic wound model, topical tripeptide-copper complex reduced wound area more than vehicle and was associated with lower TNF-alpha and MMP-2 and MMP-9 concentrations at measured time points 16

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2012;5:CD007280