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She had a history of attempting suicide and had been treated with VPA as a mood stabilizer
Off-label use typically requires private prescription
This reduces the risk of hypoglycaemia compared to some other diabetes medications, though this risk increases if used alongside insulin or sulfonylureas
Is Oral Tirzepatide Available
Maintaining electrolyte balance may be important during periods of nausea
And perhaps most relevant to this combination, hunger hormones, particularly ghrelin, tend to decrease in ketosis, reinforcing the appetite suppression that semaglutide is already creating through a completely separate pathway
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