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Appraisal results were summarized as low, moderate, or high risk of bias, and a global level of evidence was assigned using an adapted GRADE framework [12]
Peak effect at 8-12 weeks
It is supplied as a lyophilised (freeze-dried) powder to ensure optimal stability during storage and transit
Then things took a turn
Nephrolithiasis in topiramate users
It also reduces dullness and supports long-term skin health
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