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Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
Annual Review of Immunology
Key Takeaway Epitalon is considered low-risk in clinical research, with most adverse events being minor
C., Huang, Z
How the 1999 Ghrelin Discovery Reframed the Target A conceptual shift arrived in December 1999, when Kojima and colleagues at Kurume University identified ghrelin, a 28-amino-acid acylated peptide predominantly produced by gastric X/A-like cells, as the endogenous ligand for GHS-R1a
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