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The researchers used Mendelian randomization, a genetic analysis approach designed to identify potential causal relationships rather than simple correlations
Aono S, Yamada Y, Keino H, Hanada N, Nakagawa T, Sasaoka Y et al
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Usually, these FDA panels are composed of academics and researchers
It has been found that research has mostly been conducted on the animals and little evidence has been found on the canine itself, thus it should never be used in place of professional veterinary care
So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets
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