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As fasting increases ketone production with a concomitant increase in CYP2E1 activity, this in turn increases the production of NAPQI and decreases amino acid substrates for GSH production
The in vitro data is promising, the mechanism is plausible, and clinical formulations are widely available
AOD-9604 may be appropriate for individuals seeking research-based approaches to body composition optimization under physician supervision
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NICE guidance acknowledges that response to treatment varies between individuals
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