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Next, a specialized transport antiporter protein called Carnitine-Acylcarnitine Translocase (CACT) ferries this acylcarnitine complex across the impermeable inner membrane and deep into the mitochondrial matrix, while simultaneously pumping a free L-carnitine molecule back out to maintain the cycle
[1] [2] The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment
Thomas Burkes lab in the Department of Microbiology, Molecular, and Genetics
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J Clin Endocrinol Metab 104:38353850
FLOW required an eGFR between 50 and 75 mL/min/1.73 m at screening and macroalbuminuria (UACR 300 mg/g)
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