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This regulation occurs through immune response modulation, metabolic reprogramming, and intercellular interactions

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In a CY-5 experiment, replacing position 13 with Aib rendered the agonist inactive toward GCGR and slightly altered GLP-1 and GIP activity

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For future studies, it is recommended to select earlier time points and a higher frequency to assess gene expression and mitochondrial functionality of PBMC following an LPS challenge, as the primary dynamics of the immune response occur immediately after the immune challenge